组织工程用静电纺纳米纤维:所需性能

Gómez Luis Jesús Villarreal
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引用次数: 0

摘要

电纺丝纳米纤维在生物医学领域,特别是在组织工程领域受到了极大的关注,因为它具有促进细胞生长和组织愈合或再生的有趣特性,任何生物组织都可以通过选择合适的生物材料而受益。因此,这篇前瞻性文章的目的是深入了解用于组织工程方法的静电纺纳米纤维的期望性能。高拉伸强度、柔韧性、低透气性、高表面积、生物相容性和可生物降解性是组织工程应用中公认和讨论的一些更重要的特性。这些特性的目的是模拟周围组织或为目标细胞生长创造最佳条件。尽管有大量的文献报道,但仍然缺乏对上述针对各自靶组织的特性的完整筛选。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Electrospun Nanofibers for Tissue Engineering: Desired Properties
: Electrospun nanofibers have gained great attention in the biomedical industry, especially in tissue engineering, because of their interesting properties that promote cell growth and tissue cicatrization or regeneration, where any biological tissue can be beneficiated by choosing the proper biomaterials. Hence, the objective of this perspective article is to give an insight into the desired properties of the electrospun nanofibers dedicated to the tissue engineering approach. A high tensile strength, flexibility, reduced permeability of water, high surface area, biocompatibility, and biodegradability are some of the properties recognized and discussed to be more important for tissue engineering applications. The purpose of these properties is to mimic the surrounding tissue or create the optimal condition for the targeted cell growth. Despite all the reported literature, it still is missing a complete screening of the above mentioned properties specific to their respective target tissues.
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