{"title":"多相刺激的神经纤维刺激阈值","authors":"S. Beecroft, A. Alkhateeb, R. Gaumond","doi":"10.1109/NEBC.1994.305174","DOIUrl":null,"url":null,"abstract":"The authors determined the strength-duration curves for stimulus pulse waveforms of one, two, or three rectangular phases of alternating polarity. Stimuli represented the induced transmembrane current density for a voltage-clamped unmyelinated axon. For any pulse length, the one-phase pulse always required the least current density to cause an action potential, while the two-phase pulse always required the most. For short pulse lengths (</spl tausub m/, time constant for sodium gate activation at resting potential), the three-phase pulse curve approached that of the one-phase pulse; for long pulse lengths (>/spl tausub mem/, time constant of the resting membrane), the three-phase pulse curve approached that of the two-phase pulse.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"3 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Nerve fiber stimulation threshold for multiphase stimuli\",\"authors\":\"S. Beecroft, A. Alkhateeb, R. Gaumond\",\"doi\":\"10.1109/NEBC.1994.305174\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The authors determined the strength-duration curves for stimulus pulse waveforms of one, two, or three rectangular phases of alternating polarity. Stimuli represented the induced transmembrane current density for a voltage-clamped unmyelinated axon. For any pulse length, the one-phase pulse always required the least current density to cause an action potential, while the two-phase pulse always required the most. For short pulse lengths (</spl tausub m/, time constant for sodium gate activation at resting potential), the three-phase pulse curve approached that of the one-phase pulse; for long pulse lengths (>/spl tausub mem/, time constant of the resting membrane), the three-phase pulse curve approached that of the two-phase pulse.<<ETX>>\",\"PeriodicalId\":117140,\"journal\":{\"name\":\"Proceedings of 1994 20th Annual Northeast Bioengineering Conference\",\"volume\":\"3 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1994-03-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of 1994 20th Annual Northeast Bioengineering Conference\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/NEBC.1994.305174\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NEBC.1994.305174","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nerve fiber stimulation threshold for multiphase stimuli
The authors determined the strength-duration curves for stimulus pulse waveforms of one, two, or three rectangular phases of alternating polarity. Stimuli represented the induced transmembrane current density for a voltage-clamped unmyelinated axon. For any pulse length, the one-phase pulse always required the least current density to cause an action potential, while the two-phase pulse always required the most. For short pulse lengths (/spl tausub mem/, time constant of the resting membrane), the three-phase pulse curve approached that of the two-phase pulse.<>
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