{"title":"微流体中的实时基因网络控制","authors":"F. Menolascina","doi":"10.1109/ECC.2014.6862646","DOIUrl":null,"url":null,"abstract":"This tutorial paper presents two examples of invivo real-time control of gene regulatory networks in the eukaryote S. cerevisiae (baker's yeast). I discuss the theoretical and experimental challenges this problem poses and describe a microfluidics-based platform to address them. The results obtained using this setup demonstrate the proposed approach is both feasible and capable of achieving superior performances.","PeriodicalId":251538,"journal":{"name":"2014 European Control Conference (ECC)","volume":"81 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2014-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Real-time gene newtorks control in microfluidics\",\"authors\":\"F. Menolascina\",\"doi\":\"10.1109/ECC.2014.6862646\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This tutorial paper presents two examples of invivo real-time control of gene regulatory networks in the eukaryote S. cerevisiae (baker's yeast). I discuss the theoretical and experimental challenges this problem poses and describe a microfluidics-based platform to address them. The results obtained using this setup demonstrate the proposed approach is both feasible and capable of achieving superior performances.\",\"PeriodicalId\":251538,\"journal\":{\"name\":\"2014 European Control Conference (ECC)\",\"volume\":\"81 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-06-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2014 European Control Conference (ECC)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ECC.2014.6862646\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2014 European Control Conference (ECC)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ECC.2014.6862646","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
This tutorial paper presents two examples of invivo real-time control of gene regulatory networks in the eukaryote S. cerevisiae (baker's yeast). I discuss the theoretical and experimental challenges this problem poses and describe a microfluidics-based platform to address them. The results obtained using this setup demonstrate the proposed approach is both feasible and capable of achieving superior performances.