微流体中的实时基因网络控制

F. Menolascina
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引用次数: 1

摘要

本文介绍了真核生物酿酒酵母(面包酵母)基因调控网络在体内实时控制的两个例子。我讨论了这个问题带来的理论和实验挑战,并描述了一个基于微流体的平台来解决这些问题。实验结果表明,所提出的方法是可行的,并且能够取得良好的性能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Real-time gene newtorks control in microfluidics
This tutorial paper presents two examples of invivo real-time control of gene regulatory networks in the eukaryote S. cerevisiae (baker's yeast). I discuss the theoretical and experimental challenges this problem poses and describe a microfluidics-based platform to address them. The results obtained using this setup demonstrate the proposed approach is both feasible and capable of achieving superior performances.
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