纳米化学:基于纳米粒子的诊断和治疗工具箱

D. Karaman
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引用次数: 1

摘要

纳米化学是合成化学的一个方向,它关注的是如何从原子和分子的基本构建单元中构建新材料。在纳米医学的框架下,借助纳米化学方法可以提出新的自由,以创造用于治疗的纳米药物和用于诊断的纳米成像探针。在纳米化学方法的帮助下,通过调整它们的大小、形状、表面、界面和成分,可以创造出具有不同功能的纳米颗粒。纳米化学提供了削弱学科之间的界限并在全球范围内连接它们的机会。正如尼迈耶在本世纪初所描述的那样,“化学是材料研究和生物技术等应用学科发展的核心科学”[1]。在当今的研究中,纳米化学主要通过为医学提供纳米粒子,为纳米医学研究的利益缩小了生物学、化学、物理学、材料、医学、药学的界限。通过这种方式,创新的纳米颗粒设计可以解决传统医学面临的挑战和缺点。在这种情况下,纳米化学方法有助于形成基于纳米粒子的诊断和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nano-chemistry: The Toolbox for Nanoparticle Based Diagnosis and Theraphy
The direction for synthetic chemistry that focuses on the approaches to building new materials form the fundamental building units of atoms and molecules is regarded as nanochemistry. In the framework of nanomedicine, new freedoms can be proposed with the help of nano-chemistry approaches in order to create nano-pharmaceuticals for theraphy and nanoimaging probes for diagnostic. Nanoparticles with different functionalities can be created by tuning their size, shape, surfaces, interfaces, and constituents with the aid of nano-chemistry approaches. Nano-chemistry has provided the opportunity to weaken the boundaries between the disciplines and connect them globally. As already depicted by Niemeyer in the beginning of this century “chemistry is the central science for the development of applied disciplines such as materials research and biotechnology” [1]. In today’s research, nano-chemistry has contributed for diminishing the defined boundaries of biology, chemistry, physics, material, medicine, pharmacy for the benefit of nanomedicine research mainly by providing nanoparticles for medicine. By this way, innovative nanoparticle designs can address the challenges and shortcomings faced by traditional medicine. In this context, nanochemistry approaches help to form a nanoparticle-based diagnosis and theraphy.
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