Densiron-68 in the treatment of retinal detachment associated with inferior proliferative vitreoretinopathy or caused by lower or posterior breaks

Aim: The aim of this study is to demonstrate the efficacy and complications of heavy silicone oil (Densiron-68®) in the treatment of retinal detachment (RD) with inferior, posterior breaks, or associated with proliferative vitreoretinopathy (PVR). Materials and Methods: A prospective interventional noncomparative case series study of 25 eyes of 25 patients. Inclusion criteria were patients having RD arising from PVR, posterior breaks or inferior retinal breaks between 4 and 8 o'clock hours. Primary vitrectomy followed by Densiron-68 injection was performed for each patient. The study protocol involved at least 8 visits: 1st day, 1, 2, 3 weeks 1, 2, 3, and 6 months. Densiron-68 removal was performed after 2–3 months. The assessment of retinal attachment, visual acuity (VA), and complications were recorded. Results: Final anatomical success was 84% (21 of 25) cases which increased to 92% with second intervention. Mean final VA improved from mean logarithm of minimum angle of resolution of 1.89± (0.66) preoperatively to 1.094± (0.29) postoperatively. The most common complications were cataract in 60% of phakic eyes, and early emulsification in 32%. Conclusion: Densiron-68 could be used to support the lower retina in cases with RD associated with PVR, inferior, or posterior breaks. It gives a better tamponade to the inferior retina in the in the supine or upright positioning of the patient with high anatomical success rate.