2018年伊朗石油工业健康中心覆盖的老年人样本中痴呆症的职业风险因素

H. Ghassemzadeh, A. A. Kamrani, Yadollah Abolfathi Momtaz, M. Rassafiani, F. Nourhashemi, R. Sahaf, Salman Naderian
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引用次数: 0

摘要

世界上每三秒钟就有一个新的痴呆症病例。在美国,它导致的死亡人数比乳腺癌和前列腺癌加起来还要多,而在英格兰和威尔士,它是头号杀手。目前,该疾病每年造成的损失约为1万亿美元,预计到2030年将翻一番。目的:本研究的目的是确定伊朗石油工业退休人员中痴呆的可能职业和环境危险因素。方法:随机选取551名60岁及以上老年人进行病例对照研究,其中痴呆痴呆180人,非痴呆退休人员371人,学历、性别匹配。我们通过多重逻辑回归评估了痴呆风险与可能的职业和环境变量之间的关联。结果:空气污染暴露史(调整后OR=2.00, 95%CI= 1.00-7.00)、头部外伤史(调整后OR=2.00, 95%CI= 1.00-6.00)和20年以上操作领域工作史(调整后OR=5.00, 95%CI= 3.00-8.00)与痴呆风险增加显著相关。我们没有发现痴呆风险与暴露于化石燃料、溶剂、噪音污染或职业风险因素的组合之间有任何显著关联。结论:长期暴露于野外职业危险因素可能增加痴呆的发生风险。我们建议同时对石油行业的预退休人员进行一系列的颗粒物评价和适当的认知评价
本文章由计算机程序翻译,如有差异,请以英文原文为准。
OCCUPATIONAL RISK FACTORS FOR DEMENTIA IN A SAMPLE OF OLDER ADULTS COVERED BY THE IRANIAN OIL INDUSTRIES’ HEALTH CENTERS, 2018
Here is a new case of dementia in the world every three seconds. It kills more people in the US than breast cancer and prostate cancer combined, while it is the number one killer in England and Wales. The current cost of the disease is about a trillion US dollars a year, and that is forecast to double by 2030.Object: The aim of this study was to determine the probable occupational and environmental risk factors of dementia among the retirees of Iranian oil industries. Methods: A case-control study of 551 randomly selected older adults, all aged 60 and above including 180 demented and 371 nondemented retirees, pair matched for education and gender, was conducted. We evaluated the adjusted associations between dementia risk and the probable occupational and environmental variables through multiple logistic regression.Results: A history of exposure to air pollution (Adjusted OR=2.00, 95%CI= 1.00-7.00), head injuries (Adjusted OR=2.00, 95%CI= 1.00-6.00) and more than 20 years of work in the operational fields (Adjusted OR=5.00, 95%CI= 3.00-8.00) was significantly correlated with an increased risk of dementia. We could not find any significant associations between dementia risk and exposure to fossil fuels, solvents, noise pollution and or a combination of occupational risk factors. Conclusion: The results propose that long-term exposure to field occupational risk factors is likely to increase the risk of dementia. We suggest simultaneous serial oil industries’ particulate evaluations with proper cognitive assessments for the pre-retired staff
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