肝活检诊断桥本甲状腺炎合并自身免疫性肝炎1例。

Young Jun Lee, J. Sung, Sei-Hyun Kim, H. Yi, Y. Kim, Sihoon Lee, I. Park
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引用次数: 4

摘要

自身免疫性甲状腺疾病,包括桥本甲状腺炎(HT),是常见的器官特异性自身免疫性疾病,通常与其他自身免疫性疾病同时发生。自身免疫性肝炎(AIH)是一种病因不明的相对罕见的疾病。在这种情况下,肝实质发生进行性破坏。如果没有适当的免疫抑制剂治疗,如强的松和硫唑嘌呤,这种情况会导致肝硬化和肝功能衰竭。及时发现和适当治疗AIH是患者长期生存的先决条件。我们在此报告一例经肝活检证实的HT合并AIH。基于这一病例报告,我们建议,对甲状腺功能障碍纠正难治的转氨酶持续升高应进行肝活检,以区分AIH与其他形式的肝功能障碍或继发于甲状腺疾病。治疗应
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case of Hashimoto's Thyroiditis Accompanied by Autoimmune Hepatitis Diagnosed with Liver Biopsy.
Autoimmune thyroid diseases, including Hashimoto's thyroiditis (HT), are common organ-specific autoimmune disorders that often occur in conjunction with other autoimmune diseases. Autoimmune hepatitis (AIH) is a relatively rare disease of unknown etiology. In this condition, progressive destruction of the liver parenchyma occurs. Without proper treatment with immunosuppressive agents, such as prednisone and azathioprine, this condition leads to cirrhosis and liver failure. Timely detection and appropriate treatment of the AIH is prerequisite for the long-term survival of affected patients. We report here a case of HT accompanied by AIH confirmed by liver biopsy. On the basis of this case report, we suggest that, a sustained elevation of aminotransferases refractory to thyroid dysfunction correction should result in a liver biopsy to differentiate AIH from other forms of liver dysfunction or secondary to thyroid disorders. Treatment should
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