Folorunso A. Olabiyi, Yapo Guillaume Aboua, Thomas K. Monsees
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引用次数: 2
摘要
由于气候的原因,非洲大陆拥有广泛、多样和丰富的植物多样性。其中一些植物及其产品因其在治疗和管理困扰人类的疾病方面的益处而受到了极大的关注。红棕榈油(RPO)是一种天然产品,具有巨大的营养价值,能够改善心脏和生殖相关疾病。在这篇综述文章中,评价了目前关于RPO作为植物药的潜力,以减轻甚至预防肥胖对一般健康状况和男性生育能力的负面影响。本研究使用PubMed、Scopus、Science Direct、Google Scholar和Web of Science等电子数据库完成。本研究揭示了RPO对肥胖和男性生育能力影响的一些争议和不一致的报道,需要使用合适的肥胖实验模型进行进一步的研究。肥胖通过引起下丘脑-垂体-性腺轴的改变,从而损害类固醇生成和精子生成,从而破坏男性的生育能力。由于精子对氧化应激极为敏感,每天在正常饮食中谨慎均衡地补充富含抗氧化剂的RPO可能有助于保护精子和保持男性生育能力。RPO被证明是有用的,以防止或改善毒素或医疗条件引起的男性不育。此外,RPO富含强大的抗氧化剂,如类胡萝卜素和维生素E,有助于防止细胞损伤。然而,它在预防肥胖方面的作用仍存在争议。
Role of Red Palm Oil in Male Obesity and Infertility Prevention
The African continent has wide, varied, and rich plant diversity due to its climate. Some of these plants and their products have received tremendous attention due to their benefits in treating and managing ailments that plagues humanity. Red palm oil (RPO) is one of such natural products that have immense nutritional value with ability to ameliorate cardiac- and reproductive-related disorders. In this review article, the current knowledge on the potential of RPO as a phytomedicine to lessen or even prevent the negative impact of obesity on general health status and male fertility was evaluated. This study was done using electronic databases such as PubMed, Scopus, Science Direct, Google Scholar and Web of Science. The study revealed some controversies and inconsistent reports on the effect of RPO on obesity and male fertility which needs further research using appropriate experimental models of obesity. Obesity is known to disrupt male fertility by causing changes to the hypothalamic- pituitary-gonadal axis, thus impairing steroidogenesis and spermatogenesis. As spermatozoa are extremely sensitive towards oxidative stress, a carefully balanced daily supplementation of normal diet with antioxidant-rich RPO might be useful to protect spermatozoa and preserving male fertility. RPO was shown to be useful to protect against or ameliorate toxin- or medical condition-induced male infertility. Also, RPO is packed with powerful antioxidants like carotenoids and vitamin E which helps to prevent cell damage. However, its role in obesity prevention remains a debate.