In vivo measurement and visualization of fine motion without intervention by processing high-frame-rate echograms

The authors developed a method to detect in vivo fine motion inside human organs using high-speed echography, as ultrasonic imaging is the safest medical imaging technique. This method is based on high-speed digital subtraction echography, which calculates subtraction of successive echograms. By using this method, noninvasive real-time extraction of medical micromachine in the blood vessel is possible. Furthermore, making the use of blurriness of echograms, displacement length of fine motion in not only micromachine in human organ but also human organ itself is measurable. Measured motion is classified into velocity and superimposed with some colors on the original echograms according to velocity. Then we could distinguish diseased hearts from the normal heart by visualizing fine motion as colored pattern.