模拟工程组织的动态组成

Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201) Pub Date : 2001-03-31 DOI:10.1109/NEBC.2001.924731

C. Wilson, S. Kohles, L. Bonassar

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引用次数: 1

摘要

研究支架降解和新组织合成的机制对于预测工程组织的力学和生物学性能至关重要。模拟细胞-聚合物结构的动态组成可能有助于估计工程组织的长期力学性能。在这项初步研究中，我们将支架质量损失和细胞外基质合成的数学模型拟合到先前发表的数据中。

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Modeling the dynamic composition of engineered tissues

Investigation of the mechanisms underlying scaffold degradation and neotissue synthesis is essential to predicting the mechanical and biological performance of engineered tissues. Modeling the dynamic composition of cell-polymer constructs may be useful in estimating the long-term mechanical performance of the engineered tissue. In this preliminary study, we fit mathematical models of scaffold mass loss and extracellular matrix synthesis to previously published data.

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Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)

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