{"title":"研讨会07—4atypical types of dementia非典型痴呆症dementia with motor neuron disease","authors":"M. Strong, Wencheng Yang, M. Gohar, W. Strong","doi":"10.5692/CLINICALNEUROL.51.935","DOIUrl":null,"url":null,"abstract":"The neurodegenerative process of amyotrophic lateral sclerosis (ALS) includes both selective degeneration of motor neurons and one or more syndromes of frontotemporal dysfunction (e.g., behavioural (ALSbi) or cognitive(ALSci) syndromes, a frontotemporal dementia(ALS-FTD)) .There is widespread degeneration of the frontal, temporal and to a lesser extent parietal lobes in association with TDP-43 immunoreactive pathology. We have shown that tau protein metabolism is also altered in ALSci and now describe the topographic distribution of tau pathology in ALS.","PeriodicalId":371642,"journal":{"name":"Rinshō shinkeigaku Clinical neurology","volume":"298 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"シンポジウム07―4 Atypical types of dementia非典型認知症 Dementia with motor neuron disease\",\"authors\":\"M. Strong, Wencheng Yang, M. Gohar, W. Strong\",\"doi\":\"10.5692/CLINICALNEUROL.51.935\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The neurodegenerative process of amyotrophic lateral sclerosis (ALS) includes both selective degeneration of motor neurons and one or more syndromes of frontotemporal dysfunction (e.g., behavioural (ALSbi) or cognitive(ALSci) syndromes, a frontotemporal dementia(ALS-FTD)) .There is widespread degeneration of the frontal, temporal and to a lesser extent parietal lobes in association with TDP-43 immunoreactive pathology. We have shown that tau protein metabolism is also altered in ALSci and now describe the topographic distribution of tau pathology in ALS.\",\"PeriodicalId\":371642,\"journal\":{\"name\":\"Rinshō shinkeigaku Clinical neurology\",\"volume\":\"298 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rinshō shinkeigaku Clinical neurology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5692/CLINICALNEUROL.51.935\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rinshō shinkeigaku Clinical neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5692/CLINICALNEUROL.51.935","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
シンポジウム07―4 Atypical types of dementia非典型認知症 Dementia with motor neuron disease
The neurodegenerative process of amyotrophic lateral sclerosis (ALS) includes both selective degeneration of motor neurons and one or more syndromes of frontotemporal dysfunction (e.g., behavioural (ALSbi) or cognitive(ALSci) syndromes, a frontotemporal dementia(ALS-FTD)) .There is widespread degeneration of the frontal, temporal and to a lesser extent parietal lobes in association with TDP-43 immunoreactive pathology. We have shown that tau protein metabolism is also altered in ALSci and now describe the topographic distribution of tau pathology in ALS.
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