专门用于乳腺癌的PET扫描仪

R. Freifelder, J. Karp
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引用次数: 7

摘要

作者提出了一种专用于乳房成像的PET扫描仪的设计。扫描仪使用两个二维位置敏感的NaI(Tl)探测器,每个有16个pmt,放置在乳房的上方和下方来检测肿瘤。该设计结合了高空间分辨率(3.5 mm)来检测小肿瘤(/spl ap/0.1 cc),高灵敏度和良好的能量分辨率来抑制散射背景和检测低对比度的肿块。可能会对乳房和淋巴结进行额外的检查。仿真结果表明,该设计比一般的全身PET扫描仪具有更好的病灶检测能力。探测器的厚度、位置算法、NaI(Tl)和PMT排列的表面处理将确保在高状态条件下的良好性能,特别是在最靠近机身的探测器边缘。对不同的迭代重建算法在有限角度数据集上的初步研究表明,获得良好的图像质量和肿瘤可检测性是扫描仪的主要设计目标。仿真结果与初步模拟测量结果进行了比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A dedicated PET scanner for breast cancer
The authors present a design of a PET scanner dedicated to breast imaging. The scanner uses two 2-dimensional position sensitive NaI(Tl) detectors, each with 16 PMTs, placed above and below the breast to detect tumors. The design combines high spatial resolution (3.5 mm) to detect small tumors (/spl ap/0.1 cc), high sensitivity and good energy resolution to suppress scatter background and to detect low contrast masses. Additional views of the breast and lymph nodes will be possible. Simulations show that the proposed design has better lesion detectability than a general purpose whole-body PET scanner. Detector thickness, position algorithms, surface treatments of the NaI(Tl) and PMT arrangements will ensure good performance under high countrate conditions and particularly at the edges of the detector closest to the body. A preliminary investigation of different iterative reconstruction algorithms with limited angle datasets show promise in obtaining good image quality and tumor detectability, the scanner's primary design goals. Simulation results are compared to preliminary phantom measurements.
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