蜂蜜抑制四种巴贝斯虫和马氏木耳菌的体外生长

Egyptian Veterinary Medical Society of Parasitology Journal (EVMSPJ) Pub Date : 2019-06-01 DOI:10.21608/evmspj.2019.46590

M. AbouLaila

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引用次数: 1

摘要

蜂蜜具有抗氧化、免疫刺激、抗菌和抗利什曼原虫活性。在本研究中，我们评估了蜂蜜对牛巴贝斯虫、双生巴贝斯虫、发散巴贝斯虫、卡巴贝斯虫和马氏巴贝斯虫的体外杀虫和杀虫效果。0.5% (V/V)浓度对牛白僵菌、双头白僵菌、发散白僵菌和equi白僵菌的生长有明显的抑制作用，1% (V/V)浓度对caballi白僵菌的生长有明显的抑制作用。蜂蜜对牛白僵菌、双头白僵菌、发散白僵菌、小白僵菌和马僵菌的IC50值分别为1.98、1.82、0.42、1.7和1.43% (V/V)。发散芽孢杆菌的生长完全被抑制，分别为1% (V/V)、2.5% (V/V)、5% (V/V)、牛芽孢杆菌、双头芽孢杆菌和caballi芽孢杆菌。在活力试验中，分别以1% (V/V)、2.5% (V/V)、5% (V/V)的浓度抑制发散芽孢杆菌的再生，分别以2.5% (V/V)、2.5% (V/V)、5% (V/V)的浓度抑制caballi、B. bovis和B. bigemina的再生。说明蜂蜜对巴贝斯虫和马氏弓形虫具有天然杀伤作用。它在治疗临床病例中的应用需要进一步的体内评估。蜂蜜具有抗氧化、免疫刺激、抗菌和抗利什曼原虫活性。在本研究中，我们评估了蜂蜜对牛巴贝斯虫、双生巴贝斯虫、发散巴贝斯虫、卡巴贝斯虫和马氏巴贝斯虫的体外杀虫和杀虫效果。0.5% (V/V)浓度对牛白僵菌、双头白僵菌、发散白僵菌和equi白僵菌的生长有明显的抑制作用，1% (V/V)浓度对caballi白僵菌的生长有明显的抑制作用。蜂蜜对牛白僵菌、双头白僵菌、发散白僵菌、小白僵菌和马僵菌的IC50值分别为1.98、1.82、0.42、1.7和1.43% (V/V)。发散芽孢杆菌的生长完全被抑制，分别为1% (V/V)、2.5% (V/V)、5% (V/V)、牛芽孢杆菌、双头芽孢杆菌和caballi芽孢杆菌。在活力试验中，分别以1% (V/V)、2.5% (V/V)、5% (V/V)的浓度抑制发散芽孢杆菌的再生，分别以2.5% (V/V)、2.5% (V/V)、5% (V/V)的浓度抑制caballi、B. bovis和B. bigemina的再生。说明蜂蜜对巴贝斯虫和马氏弓形虫具有天然杀伤作用。它在治疗临床病例中的应用需要进一步的体内评估。

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Honey inhibits the in vitro growth of four Babesia species and Theileria equi

Honey has antioxidant, immunostimulant, antibacterial, and antileishmanial activities. In this study, we evaluated the in vitro babesicidal and theilericidal effects of honey on Babesia bovis, Babesia bigemina, Babesia divergens, Babesia caballi, and Theileria equi. There was noteworthy suppression of growth at a concentration of 0.5% (V/V) for B. bovis, B. bigemina, B. divergens, and T. equi and 1% (V/V) for B. caballi. The IC50 values of honey were 1.98, 1.82, 0.42, 1.7, and 1.43% (V/V) for B. bovis, B. bigemina, B. divergens, B. caballi, and T. equi, respectively. The growth was entirely repressed at 1% (V/V) for B. divergens,2.5% (V/V) for T. equi, and 5% (V/V) for B. bovis, B. bigemina, and B. caballi. The regrowth was repressed in the viability test at a concentration of 1% (V/V) for B. divergens,2.5% (V/V) for T. equi,and5% (V/V) for B. caballi, B. bovis,and B. bigemina. These results indicate honey as a natural killer of Babesia species and T. equi. Its use in the treatment of clinical cases requires further in vivo evaluation. Honey has antioxidant, immunostimulant, antibacterial, and antileishmanial activities. In this study, we evaluated the in vitro babesicidal and theilericidal effects of honey on Babesia bovis, Babesia bigemina, Babesia divergens, Babesia caballi, and Theileria equi. There was noteworthy suppression of growth at a concentration of 0.5% (V/V) for B. bovis, B. bigemina, B. divergens, and T. equi and 1% (V/V) for B. caballi. The IC50 values of honey were 1.98, 1.82, 0.42, 1.7, and 1.43% (V/V) for B. bovis, B. bigemina, B. divergens, B. caballi, and T. equi, respectively. The growth was entirely repressed at 1% (V/V) for B. divergens,2.5% (V/V) for T. equi, and 5% (V/V) for B. bovis, B. bigemina, and B. caballi. The regrowth was repressed in the viability test at a concentration of 1% (V/V) for B. divergens,2.5% (V/V) for T. equi,and5% (V/V) for B. caballi, B. bovis,and B. bigemina. These results indicate honey as a natural killer of Babesia species and T. equi. Its use in the treatment of clinical cases requires further in vivo evaluation.

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Egyptian Veterinary Medical Society of Parasitology Journal (EVMSPJ)

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