用T2滤光片成像多发性硬化症的病灶内异质性

R. Gabr, P. Narayana
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引用次数: 0

摘要

多发性硬化症(MS)病变异质性的磁共振成像可以区分神经损伤的严重程度,并为MS病变的进展提供见解。我们提出了一种基于双回波自旋回波磁共振成像获得的脑横向弛豫时间(T2)值来显示病变异质性的新方法。我们表明,病变不同组成部分的可视化可以通过T2滤波器增强,该滤波器可以消除中等延长的T2值。在7例MS患者中,重建的t2滤波图像显示出暗和亮的强度区域,可能分别对应轻度和重度组织损伤,这与之前的代数方法产生的结果相似。所提出的滤波器为表征多发性硬化症病变的异质性提供了一个更简单和有见地的公式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Imaging Intralesional Heterogeneity in Multiple Sclerosis using a T2 Filter
Magnetic resonance imaging of lesion heterogeneity in multiple sclerosis (MS) allows the discrimination of the severity of neural injury, and provides insight into the progression of the MS lesions. We propose a new method to visualize lesion heterogeneity based on the brain transverse relaxation time (T2) values obtained from dual-echo spin-echo magnetic resonance imaging. We show that visualization of the different components of the lesion can be enhanced using a T2 filter that nulls moderately prolonged T2 values. In seven MS patients, the reconstructed T2-filtered images showed regions of dark and bright intensity, presumably corresponding to mild and severe tissue injury, respectively, which were similar to those produced by a previous algebraic method. The proposed filter provides a simpler and insightful formulation for characterizing MS lesion heterogeneity.
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