老年人可能不适当的药物处方:美国老年医学会更新了啤酒标准之旅

Rishabh Sharma, P. Bansal, R. Garg, M. Arora
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引用次数: 1

摘要

目前的手稿突出了比尔斯的指导方针,直到今天,并把它们放在一个单一的平台上,使医生,学者和患者能够安全和及时地使用药物。潜在不适当药物(PIM)是指不良风险超过其健康益处的药物。老年人的复杂和多重合并症使他们使用多种药物,这进一步成为被排除在随机临床试验(RCT)之外的原因。因此,没有固定的指导方针或基于随机对照试验的科学证据来支持处方决定。PIM在老年人中已经成为越来越普遍的问题;因此,美国老年医学会更新了比尔斯的标准;检查其使用/误用的最关键策略。比尔斯标准于1991年在经过验证和适当的筛选工具的帮助下制定,这些工具根据老年人的健康状况解释了各种药物的使用/避免情况,并在需要时进一步更新。比尔斯标准的改变是由于研究人群的一些局限性,新出现的药物不良反应/新药物分子,药物的药效学随着老年人生理变化而变化。啤酒指南正在更新;然而,负责制定标准的委员会几乎没有涉及到重大问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Potentially inappropriate medication prescribing in older adults: American geriatric society updated beers criteria journey
The present manuscript highlights Beers guidelines till date and puts them at a single platform to enable the physicians, academicians, and patients for the safe and timely use of medicines. Potentially inappropriate medications (PIM) are medications in which adverse risks exceed its health benefits. Complex and multiple comorbidities in older adults make them use multiple drugs that further become a reason for exclusion from randomized clinical trials (RCT). Hence, no set guidelines or RCT-based scientific shreds of evidence are available to support prescription decisions. PIM has become an increasingly common problem in older adults; hence the American Geriatric Society updated Beers criteria; the most crucial strategy to check its use/misuse. The Beers criteria have been formulated in 1991 with the help of validated and appropriate screening tools that explain the use/avoidance of various drugs in older adults based on their health status and are being further updated as and when required. This change in Beers criteria is due to some limitations in the study population, emerging adverse drug reactions/new drug molecules, change in pharmacodynamics of medicines with changing physiology of older adults. Beers guidelines are being updated; however, few significant issues that are not being touched by the committee responsible for constituting the criteria.
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