自身免疫性甲状腺炎的现代治疗方法

F. Sadikhov
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摘要

这个问题的相关性是由于发病率的不断增加和现有治疗方法的有效性不足。本研究旨在通过引进现代激光技术提高自身免疫性甲状腺炎患者的治疗效果。该研究从2008年至2021年进行回顾性研究,基于481例自身免疫性甲状腺炎患者的检查和治疗数据。根据采用的治疗方法将患者分为三组:第一组129例(29.19%),第二组106例(23.98%),第三组207例(46.83%)。研究并比较治疗前后患者血清中甲状腺激素、垂体及甲状腺组织抗体的浓度。对340例(76.7%)患者的长期治疗结果进行了研究(t=8,8, p≤0.001)。光动力疗法,结合低强度激光照射的静脉激光血液照射,有助于在治疗第15天甲状腺激素水平(TSH, FT4和FT3)的正常化。自身免疫性甲状腺炎患者保守治疗与光动力治疗相结合,77.5%的病例可获得良好满意的结果,因此推荐光动力治疗联合低强度激光静脉血液照射作为传统保守治疗的有效补充
本文章由计算机程序翻译,如有差异,请以英文原文为准。
MODERN ASPECTS OF THE TREATMENT OF PATIENTS WITH AUTOIMMUNE THYROIDITIS
The relevance of the problem is due to the continuous increase in morbidity and the lack of effectiveness of existing treatment methods. The aim of the study is to improve the treatment results of patients with autoimmune thyroiditis by introducing modern laser technology. The study was conducted retrospectively from 2008 to 2021 and is based on data from the examination and treatment of 481 patients with autoimmune thyroiditis. The patients were divided into groups according to the applied treatment methods: the first group - 129 (29,19%) patients, the second group - 106 (23,98%) patients, and the third group - 207 (46,83%) patients. The concentrations of thyroid hormones, pituitary gland and antibodies to thyroid tissues in the blood serum of patients before and after treatment were studied and compared. Long-term treatment results were studied in 340 (70,7%) patients (t=8,8, p≤0,001). Photodynamic therapy, in combination with sessions of intravenous laser blood irradiation with lowintensity laser radiation, contributed to the normalization of thyroid hormone levels (TSH, FT4 and FT3) of the thyroid gland on the 15th day of treatment. Combining conservative treatment of patients with autoimmune thyroiditis with photodynamic therapy allows to obtain good and satisfactory results in 77,5% of cases, which gives reason to recommend photodynamic therapy in combination with sessions of intravenous laser blood irradiation with low-intensity laser radiation as an effective way to complement traditional conservative treatment
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