Howdah -分析基因组数据的灵活管道框架

2010 IEEE Second International Conference on Cloud Computing Technology and Science Pub Date : 2010-11-30 DOI:10.1109/CloudCom.2010.75

Steven Lewis, Sheila M. Reynolds, Hector Rovira, Mike O'Leary, S. Killcoyne, I. Shmulevich, J. Boyle

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引用次数: 0

摘要

新的高通量测序技术的出现导致了大量的基因组数据，这压倒了单处理器机器的能力。我们提出了一个名为Howdah的MapReduce管道，它支持基因组序列数据的分析，允许在单个MapReduce作业中插入多个测试。该管道用于检测染色体异常，如插入，缺失和易位以及单核苷酸多态性(snp)。

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Howdah - A Flexible Pipeline Framework for Analyzing Genomic Data

The advent of new high-throughput sequencing technologies has led to a flood of genomic data which overwhelms the capabilities of single processor machines. We present a MapReduce pipeline called Howdah that supports the analysis of genomic sequence data allowing multiple tests to be plugged in to a single MapReduce job. The pipeline is used to detect chromosomal abnormalities such as insertions, deletions and translocations as well as single nucleotide polymorphisms (SNPs).

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2010 IEEE Second International Conference on Cloud Computing Technology and Science

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