对称模式在DNA序列功能位点识别和系统发育分析中的应用

N. Akberova, L. Yu
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引用次数: 0

摘要

从对称的角度分析了参与复制起始的一组遗传文本。与表型分类相对应的子集被发现包含相同的对称结构。除了传统的对称性(潜在的发夹、直接重复和反向重复)外,在相关序列中发现了嘌呤-嘧啶重复和氨基酮重复的相等距离。在对称结构中,已经确定了复制蛋白结合位点以及参与转录起始的位点。结果表明,对称分析在解决遗传文本模式识别问题上是有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Application of symmetry patterns to recognition of functional sites and phylogenetic analysis of DNA sequences
The set of genetic texts, taking part in replication initiation has been analyzed from the point of view of their symmetry. The subsets, corresponding to the phenotypical classification, were found to contain the same symmetrical structures. Along with the traditional symmetries (potential hairpins, direct and inverted repeats) the purine-pyrimidine and aminoketo repeats were found at equal distances in related sequences. Among the symmetrical structures the replication protein binding sites have been identified as well as sites taking part in the transcription initiation. The results obtained show the efficiency of symmetrical analysis in solving the problem of pattern recognition in genetic text.
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