{"title":"药物发现:科学还是艺术?","authors":"D. Liberati","doi":"10.31038/jppr.2018112","DOIUrl":null,"url":null,"abstract":"One of the reason for such healthy and wealthy attitude is that drug discovery is not obvious nor simple nor cheap nor fast, as a rule: a good chemical could imply a fortune even in the few years of validity of the patent. A thorough knowledge of pathophysiology is required in order to design biochemistry able to heal without damaging to much. Intuition and experience are paramount, but nowadays at least a couple of approaches are keen to help.","PeriodicalId":285318,"journal":{"name":"Journal of Pharmacology & Pharmaceutical Research","volume":"195 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Drug discovery: science and/or art?\",\"authors\":\"D. Liberati\",\"doi\":\"10.31038/jppr.2018112\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"One of the reason for such healthy and wealthy attitude is that drug discovery is not obvious nor simple nor cheap nor fast, as a rule: a good chemical could imply a fortune even in the few years of validity of the patent. A thorough knowledge of pathophysiology is required in order to design biochemistry able to heal without damaging to much. Intuition and experience are paramount, but nowadays at least a couple of approaches are keen to help.\",\"PeriodicalId\":285318,\"journal\":{\"name\":\"Journal of Pharmacology & Pharmaceutical Research\",\"volume\":\"195 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-06-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pharmacology & Pharmaceutical Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31038/jppr.2018112\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmacology & Pharmaceutical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31038/jppr.2018112","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
One of the reason for such healthy and wealthy attitude is that drug discovery is not obvious nor simple nor cheap nor fast, as a rule: a good chemical could imply a fortune even in the few years of validity of the patent. A thorough knowledge of pathophysiology is required in order to design biochemistry able to heal without damaging to much. Intuition and experience are paramount, but nowadays at least a couple of approaches are keen to help.
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