SPERTL:利用脑电图与ResNets和迁移学习预测癫痫发作

Umair Mohammad, Fahad Saeed
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引用次数: 0

摘要

癫痫是一种慢性疾病,可引起反复无端发作,许多癫痫患者要么对药物产生耐药性,要么不适合手术治疗。因此,这些反复出现的不可预测的癫痫发作可能对生活质量产生严重的负面影响,包括受伤风险增加、社会污名化、无法参加驾驶等基本活动,并可能减少获得医疗保健的机会。一个预测系统,通知患者和护理人员的潜在即将到来的癫痫发作提前不仅是可取的,而且是迫切需要的。在本文中,我们通过设计和开发仅使用残差神经网络(ResNets)和迁移学习(TL) - (SPERTL)的脑电图(EEG)数据的患者特异性癫痫发作(ES)预测模型做出贡献。我们对20例癫痫发作预测期(SPH)为5分钟的脑电图数据进行了训练,并利用验证数据绘制了准确率-召回率曲线,以选择最佳阈值。对未见数据的测试表明,我们的模型优于最先进的方法,达到最高的平均灵敏度为88.1%,特异性为92.3%,准确性为92.3%。我们的结果还表明,所提出的模型在保持高阳性预测率的同时,更不易受到假阳性的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SPERTL: Epileptic Seizure Prediction using EEG with ResNets and Transfer Learning
Epilepsy is a chronic condition that causes repeat unprovoked seizures and many epileptics either develop resistance to medications and/or are not suitable candidates for surgical solutions. Hence, these recurring unpredictable seizures can have a severely negative impact on quality of life including an elevated risk of injury, social stigmatization, inability to take part in essential activities such as driving and possibly reduced access to healthcare. A predictive system that informs patients and caregivers about a potential upcoming seizure ahead of time is not only desirable but an urgent necessity. In this paper, we contribute by designing and developing patient-specific epileptic seizure (ES) prediction models using only electroencephalography (EEG) data with residual neural networks (ResNets) and transfer learning (TL) - (SPERTL). We train our proposed model on EEG data from 20 patients with a seizure prediction horizon (SPH) of 5 minutes and use the validation data to plot precision-recall curves for selecting the best thresholds. Testing on unseen data shows our model outperforms the state-of-the-art methods by achieving the highest average sensitivity of 88.1%, specificity of 92.3%, and accuracy of 92.3%. Our results also demonstrate the proposed model is less susceptible to false positives while maintaining a high positive prediction rate.
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