{"title":"鼻咽部髓外浆细胞瘤1例并文献复习","authors":"A. Aluko, Ghazali Hasheem, A. Auwal","doi":"10.4081/PJM.2019.52","DOIUrl":null,"url":null,"abstract":"Plasmocytoma is a monoclonal neoplasm derived from progenitor B lymphocyte lineage. It rarely occurs as solitary plasmacytoma in 5-10% of all plasma cell tumors. Extramedullary plasmacytoma is even rarer, accounting for 3% of solitary plasmacytoma. Extramedullary plasmacytoma of the nasopharynx was found to be the cause of emergency presentation with upper airway obstruction and dysphagia in a 50 years old man. The patient had an emergency tracheostomy and feeding gastrostomy. Tumor biopsy and histology confirmed plasmacytoma. He was treated with chemoradiation without prior surgical excision and he had satisfactory improvement. This report highlights that a high index of suspicion is needed for early diagnosis and prompt treatment.","PeriodicalId":430358,"journal":{"name":"Pyramid Journal of Medicine","volume":"118 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Extramedullary plasmacytoma of the nasopharynx: A case report and review of literature\",\"authors\":\"A. Aluko, Ghazali Hasheem, A. Auwal\",\"doi\":\"10.4081/PJM.2019.52\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Plasmocytoma is a monoclonal neoplasm derived from progenitor B lymphocyte lineage. It rarely occurs as solitary plasmacytoma in 5-10% of all plasma cell tumors. Extramedullary plasmacytoma is even rarer, accounting for 3% of solitary plasmacytoma. Extramedullary plasmacytoma of the nasopharynx was found to be the cause of emergency presentation with upper airway obstruction and dysphagia in a 50 years old man. The patient had an emergency tracheostomy and feeding gastrostomy. Tumor biopsy and histology confirmed plasmacytoma. He was treated with chemoradiation without prior surgical excision and he had satisfactory improvement. This report highlights that a high index of suspicion is needed for early diagnosis and prompt treatment.\",\"PeriodicalId\":430358,\"journal\":{\"name\":\"Pyramid Journal of Medicine\",\"volume\":\"118 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-07-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pyramid Journal of Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4081/PJM.2019.52\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pyramid Journal of Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4081/PJM.2019.52","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Extramedullary plasmacytoma of the nasopharynx: A case report and review of literature
Plasmocytoma is a monoclonal neoplasm derived from progenitor B lymphocyte lineage. It rarely occurs as solitary plasmacytoma in 5-10% of all plasma cell tumors. Extramedullary plasmacytoma is even rarer, accounting for 3% of solitary plasmacytoma. Extramedullary plasmacytoma of the nasopharynx was found to be the cause of emergency presentation with upper airway obstruction and dysphagia in a 50 years old man. The patient had an emergency tracheostomy and feeding gastrostomy. Tumor biopsy and histology confirmed plasmacytoma. He was treated with chemoradiation without prior surgical excision and he had satisfactory improvement. This report highlights that a high index of suspicion is needed for early diagnosis and prompt treatment.