Моноаминоксидазные и симпатолитические свойства некоторых производныхα, β – дегидротирозина

New synthesized derivatives of (5Z)-5-(3-ethoxy-4-hydroxybenzyliden)-2-phenyl-3,5-dihydro-4H-imidazol-4-one and benzamides with antimonoaminooxidase and sympatholytic properties were studied. Studies showed that the compounds exhibit antimonoaminooxidase activity, inhibiting the deamination of serotonin, and sympatholytic action by blocking of α1-adrenoreceptors. The obtained data indicate the possibility of creating new antidepressant preparations based on monoaminoxidase (MAO) inhibitors, having simultaneous sympatholytic properties. These drugs will be much safer due to a decrease in the risk of arterial hypertension.