{"title":"利用宽场干涉散射显微镜成像纳米颗粒与细胞膜的结合","authors":"Hengze You, C. L. Anyi, Liaoliao Wei, Tong Ling","doi":"10.1364/omp.2023.oth1e.2","DOIUrl":null,"url":null,"abstract":"We applied iSCAT microscopy to image the Brownian movement of nanoparticles in live cell culture. Utilizing autocorrelation analysis, we demonstrated mapping of nanoparticle binding interactions with the plasma membrane in a wide field.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"12 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Imaging Nanoparticle Binding to Cell Membrane through Wide-field Interferometric Scattering Microscopy\",\"authors\":\"Hengze You, C. L. Anyi, Liaoliao Wei, Tong Ling\",\"doi\":\"10.1364/omp.2023.oth1e.2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We applied iSCAT microscopy to image the Brownian movement of nanoparticles in live cell culture. Utilizing autocorrelation analysis, we demonstrated mapping of nanoparticle binding interactions with the plasma membrane in a wide field.\",\"PeriodicalId\":111173,\"journal\":{\"name\":\"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)\",\"volume\":\"12 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1364/omp.2023.oth1e.2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/omp.2023.oth1e.2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Imaging Nanoparticle Binding to Cell Membrane through Wide-field Interferometric Scattering Microscopy
We applied iSCAT microscopy to image the Brownian movement of nanoparticles in live cell culture. Utilizing autocorrelation analysis, we demonstrated mapping of nanoparticle binding interactions with the plasma membrane in a wide field.