病例对照研究

A. Soto, A. Cvetkovic-Vega
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摘要

病例对照研究是分析性观察性流行病学研究,通常致力于评价与罕见疾病相关的因素。它在证据金字塔中的等级位于横断面研究和队列研究之间的中间位置。这些研究中使用的关联度量是优势比。这种设计的一些变体,如事件和嵌套案例研究以及嵌套病例对照研究(在队列中)可以减少选择偏倚的风险。本文回顾了与这类研究相关的基本概念。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Case–Control Studies
Case-control studies are analytical observational epidemiological studies generally devoted to evaluate factors associated with infrequent diseases. Its hierarchy within the pyramid of evidence lies in an intermediate place between cross sectional and cohort studies. The measure of association used for these studies is the Odds Ratio. Some variants of this design, such as incident and nested case studies and nested case-control studies (within a cohort) can reduce the risk of selection bias. The basic concepts related to this type of studies are reviewed.
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