T. Solvik, Tan A Nguyen, Yu-Hsiu Tony Lin, Timothy Marsh, E. Huang, A. Wiita, Jayanta Debnath, Andrew M. Leidal
{"title":"分泌性自噬在溶酶体抑制下维持蛋白静止","authors":"T. Solvik, Tan A Nguyen, Yu-Hsiu Tony Lin, Timothy Marsh, E. Huang, A. Wiita, Jayanta Debnath, Andrew M. Leidal","doi":"10.1083/jcb.202110151","DOIUrl":null,"url":null,"abstract":"Solvik et al. reveal that the autophagy machinery facilitates the secretion of autophagy cargo receptors and other cellular components via extracellular vesicles and particles in response to lysosome inhibition or impaired autophagosome maturation.","PeriodicalId":343306,"journal":{"name":"The Journal of Cell Biology","volume":"211 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"46","resultStr":"{\"title\":\"Secretory autophagy maintains proteostasis upon lysosome inhibition\",\"authors\":\"T. Solvik, Tan A Nguyen, Yu-Hsiu Tony Lin, Timothy Marsh, E. Huang, A. Wiita, Jayanta Debnath, Andrew M. Leidal\",\"doi\":\"10.1083/jcb.202110151\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Solvik et al. reveal that the autophagy machinery facilitates the secretion of autophagy cargo receptors and other cellular components via extracellular vesicles and particles in response to lysosome inhibition or impaired autophagosome maturation.\",\"PeriodicalId\":343306,\"journal\":{\"name\":\"The Journal of Cell Biology\",\"volume\":\"211 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-04-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"46\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Cell Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1083/jcb.202110151\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Cell Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1083/jcb.202110151","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Secretory autophagy maintains proteostasis upon lysosome inhibition
Solvik et al. reveal that the autophagy machinery facilitates the secretion of autophagy cargo receptors and other cellular components via extracellular vesicles and particles in response to lysosome inhibition or impaired autophagosome maturation.