Abstract

Radiotherapy for brain tumors with hair follicle protection for alopecia reduction has become a viable option with the introduction of inverse planning radiotherapy techniques. The aim of the study was the evaluation of the possibility of reducing the maximum and the medium dose received by the scalp for 3 cases of temporoparietal glioblastoma patients irradiated with a total dose of 60Gy and the effect of applying this constraint on other radiosensitive anatomical structures. In all three cases a reduction in mean doses of 5.5%, 3.2% and 12.5% was achieved using the modulated intensive radiotherapy technique (IMRT) and 5.1%, 0.8% and 22.2% by volumetric modulated arc therapy (VMAT) and a reduction of maximum dose by 18.7%, 9.6% and 8.3% using IMRT technique and by 16.35%, 11% and 16% using VMAT technique with no increase in dose to the other radiosensitive organs including hippocampus involved in cognitive function of patients.