定量分析生命系统的调节机制,以确定异常期间的有效影响点

M. Saidalieva, M. Hidirova
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引用次数: 4

摘要

本文对生命系统的调控机制进行建模,以识别异常时的有效调控点。计算实验表明,在一定的胞内和胞外条件下,存在如下状态:稳态、自振荡和混沌行为、“黑洞”效应、“r窗口”。结果表明,在异常区域(动态混沌和“黑洞”区域),最优的“处理策略”是过渡到最近的不规则振荡“r窗口”,或在最小化不规则水平和代谢负荷的情况下,沿着“r窗口”链依次过渡到极限环区域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quantitative analysis of the regulatory mechanisms of living systems to identify effective influence points during anomalies
This paper deals with modeling the regulatory mechanisms of living systems to identify effective regulatory points during anomalies. Computational experiments show that at certain values of internal and external cellular conditions there are exist the following regimes: stationary state, auto-oscillations and chaotic behavior, “black hole” effect, “r-windows”. The results showed that in the anomaly areas (dynamic chaos and “black hole” area), the most optimal “treatment strategy” is the transition to the nearest “r-windows” of irregular oscillations or a sequential transition along the chain from “r-windows” to the region of limit cycles using minimization of irregularity levels and metabolic load.
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