再入重症监护的肺移植患者的ICU预后和生活质量

Dr. Rajesh Mohan Shetty
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摘要

在肺移植受者中,入住ICU是比较常见的。据报道,ICU每次入院的死亡率约为37%。本研究的目的是评估需要再次入住ICU的肺移植患者的患者特征、ICU预后和生活质量。回顾性收集首次ICU再入院患者的ICU资料。采用SF36v2工具前瞻性评估生活质量。研究对象:63例再次入住ICU的肺移植受者组成研究组。通过计算机随机数生成器软件选择66例同时行移植手术且移植后未再次入住ICU的患者作为对照组。问卷的回应率为70%。ICU平均生存时间为4.53天(SD 4.68)。机械通气的平均持续时间为3.83天(SD 4.03)。研究组的总死亡率为21%,对照组为9% (p = 0.08)。与澳大利亚标准相比,研究人群的SF36v2评分较低。研究组和对照组的PCS总结平均得分分别为42.21 (SD 12.81)和45.32 (SD 11.28),差异有统计学意义(p= 0.267); MCS平均得分分别为45.68 (SD 12.37)和47.79 (SD 9.25),差异有统计学意义(p= 0.410)。需要再次入住ICU的肺移植患者的总死亡率更高(p= 0.08)。与不需要再入ICU的患者相比,存活的患者具有良好的ICU预后和相似的生活质量评分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ICU Outcomes and Quality of Life in Lung Transplant Patients Readmitted to Intensive care
Admission to the ICU is relatively common in lung transplant recipients. The ICU mortality rate has been reported to be around 37% per admission. The aim of our study was to assess patient characteristics, ICU outcomes and QOL of lung transplant patients who required ICU readmission. ICU data from the first ICU readmission were collected retrospectively. QOL was assessed using SF36v2 tool prospectively. Cardiopulmonary transplant centre Participants: 63 lung transplant recipients who were readmitted to ICU formed the study group. 66 patients selected by computer random number generator software who underwent transplant at the same time but were not readmitted to ICU after transplant formed the control group. The response rate to the questionnaire was 70%. Mean ICU LOS was 4.53 (SD 4.68) days. Mean duration of mechanical ventilation was 3.83 (SD 4.03) days. Overall mortality was 21% in the study group and 9% in the control group (p = 0.08). SF36v2 scores were lower in the study population compared to Australian norms. The mean PCS summary scores for study group and control groups were 42.21 (SD 12.81) and 45.32 (SD 11.28) respectively (p = 0.267) and that for the mean MCS were 45.68 (SD 12.37) and 47.79 (SD 9.25) respectively (p= 0.410). Lung transplant patients requiring ICU readmission had higher overall mortality (p= 0.08). Those patients who survived had good ICU outcomes and similar QOL scores compared to those who did not require ICU readmission.
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