生物医学应用中多孔人工制品的表示

Craig A. Schroeder, W. Regli, A. Shokoufandeh, Wei Sun
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引用次数: 8

摘要

非均质结构是21世纪工程领域一个重要的新领域。例如,组织工程结构,如用于引导组织再生的骨支架,可以被描述为由3D细胞外基质(由可生物降解材料制成)和种子供体细胞和/或生长因子组成的异质结构。这种异质结构的设计和制造需要新的实体模型技术来表示具有复杂材料特性的三维异质物体。本文提出了一种基于随机几何的模型密度和孔隙度表示方法。虽然之前的文献已经对密度进行了研究,但孔隙度是生物医学CAD的一个新问题,对模拟替代骨组织至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Representation of porous artifacts for bio-medical applications
Heterogeneous structures represent an important new frontier for 21st century engineering. For instance, a tissue engineered structure, such as bone scaffold for guided tissue regeneration, can be described as a heterogeneous structure consisting of 3D extra-cellular matrices (made from biodegradable material) and seeded donor cells and/or growth factors. The design and fabrication of such heterogeneous structures requires new techniques for solid models to represent 3D heterogeneous objects with complex material properties. This paper presents a representation of model density and porosity based on stochastic geometry. While density has been previously studied in the literature, porosity is a new problem for bio-medical CAD critical for modeling replacement bone tissues.
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