MiR‐6838‐5p通过靶向WNT3A抑制Wnt通路，抑制三阴性乳腺癌的细胞转移和EMT过程

The Journal of Gene Medicine Pub Date : 2019-11-06 DOI:10.1002/jgm.3129

Guozhu Liu, ping wang, Hao Zhang

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引用次数: 24

摘要

三阴性乳腺癌(Triple‐negative breast cancer, TNBC)具有复发相对较快、脑转移发生率高的特点，已成为危害女性身心健康的常见肿瘤。越来越多的研究表明，microrna在TNBC的进展中起着关键作用。然而，miR - 6838 - 5p在TNBC中的功能尚未报道，需要进一步探索。

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MiR‐6838‐5p suppresses cell metastasis and the EMT process in triple‐negative breast cancer by targeting WNT3A to inhibit the Wnt pathway

Triple‐negative breast cancer (TNBC) has become a common tumor that harms women's physical and mental health, as characterized by a relatively rapid recurrence and a high incidence of brain metastasis. Research increasingly suggests that microRNAs play key roles in the progress of TNBC. However, the function of miR‐6838‐5p in TNBC has not yet been reported, and requires additional exploration.

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The Journal of Gene Medicine

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