微流体免疫分析肺泡细胞释放白介素-8使用盲文显示计算机控制的流体驱动

Y. Kamotani, W. Gu, N. Futai, S. Takayama
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引用次数: 1

摘要

我们开发了一种独立的、无连接的、自动化的微流控免疫分析系统,用于检测和量化白细胞介素(IL)-8的水平,IL -8是一种参与炎症反应的重要细胞因子。在我们的微流体系统中,液体流动是使用市售的、可刷新的盲文显示器的引脚来控制的,该显示器充当小型机械执行器。这种微系统的成功开发将有助于各种疾病状态的早期诊断和治疗。将微流控免疫分析系统与细胞培养相结合,可以提供一种新的、独立的设备来分析受控微环境中化学刺激细胞的副产物
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microfluidic Immunoassay for Alveolar Cell Released Interleukin-8 Using a Braille Display for Computer-Controlled Fluid Actuation
We have developed a self-contained, connectorless, automated microfluidic immunoassay system to detect and quantify levels of Interleukin (IL)-8, an important cytokine involved in the inflammatory response. In our microfluidic system, liquid flow is controlled using the pins of a commercially available, refreshable Braille display that act as small mechanical actuators. The successful development of such a microsystem will prove beneficial in both the early diagnosis and treatment of various disease states. Integration of the microfluidic immunoassay system with cell culture can provide a novel, self-contained device to analyze the by-products of chemically stimulated cells in a controlled microenvironment
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