大葱提取物对FST模型小鼠乳酸水平的影响

A. Ramadhani, Muchsin Doewes, S. Listyawati
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引用次数: 0

摘要

剧烈的体育锻炼可以增加血液中的乳酸水平,因为此时发生的无氧代谢。乳酸水平增加的影响包括酸中毒的发生,对身体细胞的损害和疲劳,从而降低肌肉的表现。抗氧化剂可以起到预防氧化应激引起的身体疲劳的作用。葱属植物(Eleutherine palmifolia)是一种有益健康的药用植物。大葱中抗氧化剂含量高,可作为抗疲劳的替代成分。本研究旨在观察大葱提取物的剂量和持续时间对小鼠强迫游泳试验模型乳酸水平和身体活动的影响。研究类型试验前后随机对照组设计。雄性白鼠(Sprague Dawley) 2月龄(体重150-200g)。分为5组,K-组(实验组不给予大雅葱提取物,仍给予FST)、K+组(实验组给予黄嘌呤和FST)、P1组(给予大雅葱提取物50mg/200gBW)、P2组(给予大雅葱提取物100mg/200gBB)、P3组(给予洋葱提取物200mg/200gBW)。给药28 d后进行强迫游泳试验,观察大鼠游泳时乳酸和体力活动耐力的变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effect of Dayak Onion Extract on Lactic Acid Levels in Mice with FST Model
Intense physical exercise can increase lactic acid levels in the blood as a result of the anaerobic metabolism that occurs at that time. The impact of increased levels of lactic acid includes the occurrence of acidosis, damage to body cells, and fatigue which reduces muscle performance. Antioxidants can play a role in preventing body fatigue caused by oxidative stress. Onion Dayak (Eleutherine palmifolia) is a type of medicinal plant that is useful for health. The high content of antioxidants in Dayak onions can be used as an alternative anti-fatigue ingredient. This study aimed to look at the effect of the dose and duration of Dayak onion extract on lactic acid levels and physical activity in mice forced swimming test models. Type of Research Randomized Pre and Post-Test Control Group Design. Male White Mice (Sprague Dawley) 2 months old (weight 150-200g). Divided into 5 groups K- (the experimental group was not given Dayak onion extract, they were still given FST), K+ (the experimental group was given xanthine and FST), P1 (given Dayak onion extract at a dose of 50mg/200gBW), P2 (given the extract onion Dayak dose of 100mg/200gBB), P3 (given onion extract dose of 200mg/200gBW). Dayak onion extract was given for 28 days and given the forced swimming test, then the changes in lactic acid and physical activity endurance in swimming were observed.
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