金纳米颗粒在癌症成像和治疗中的应用

Shouju Wang, Guangming Lu
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引用次数: 20

摘要

癌症是世界范围内导致死亡的主要原因之一。在过去的二十年里,纳米技术的发展促进了我们设计用于诊断和治疗癌症的新型纳米粒子的能力。在本章中,我们综述了金纳米颗粒作为造影剂在癌症成像中的应用,包括光学成像、光声成像和x射线成像。我们还综述了它们作为小分子药物、治疗基因、疫苗和佐剂的递送载体以及作为治疗剂在癌症治疗中的应用,包括光热治疗、光动力治疗和放射治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Applications of Gold Nanoparticles in Cancer Imaging and Treatment
Cancer is one of the leading causes of death worldwide. In the last two decades, the development of nanotechnology has facilitated our ability to design new nanoparticles for the diagnosis and treatment of cancer. In this chapter, we reviewed the applications of gold nanoparticles as contrast agents for cancer imaging, including optical imaging, photoacoustic imaging, and X-ray–based imaging. We also reviewed their applications as delivery carriers for small molecule drugs, therapeutic genes, vaccines, and adjuvants and as therapeutic agents by themselves in cancer treatment, including photothermal therapy, photodynamic therapy, and radiation therapy.
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