{"title":"金纳米颗粒在癌症成像和治疗中的应用","authors":"Shouju Wang, Guangming Lu","doi":"10.5772/INTECHOPEN.70901","DOIUrl":null,"url":null,"abstract":"Cancer is one of the leading causes of death worldwide. In the last two decades, the development of nanotechnology has facilitated our ability to design new nanoparticles for the diagnosis and treatment of cancer. In this chapter, we reviewed the applications of gold nanoparticles as contrast agents for cancer imaging, including optical imaging, photoacoustic imaging, and X-ray–based imaging. We also reviewed their applications as delivery carriers for small molecule drugs, therapeutic genes, vaccines, and adjuvants and as therapeutic agents by themselves in cancer treatment, including photothermal therapy, photodynamic therapy, and radiation therapy.","PeriodicalId":201297,"journal":{"name":"Noble and Precious Metals - Properties, Nanoscale Effects and Applications","volume":"14 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"20","resultStr":"{\"title\":\"Applications of Gold Nanoparticles in Cancer Imaging and Treatment\",\"authors\":\"Shouju Wang, Guangming Lu\",\"doi\":\"10.5772/INTECHOPEN.70901\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cancer is one of the leading causes of death worldwide. In the last two decades, the development of nanotechnology has facilitated our ability to design new nanoparticles for the diagnosis and treatment of cancer. In this chapter, we reviewed the applications of gold nanoparticles as contrast agents for cancer imaging, including optical imaging, photoacoustic imaging, and X-ray–based imaging. We also reviewed their applications as delivery carriers for small molecule drugs, therapeutic genes, vaccines, and adjuvants and as therapeutic agents by themselves in cancer treatment, including photothermal therapy, photodynamic therapy, and radiation therapy.\",\"PeriodicalId\":201297,\"journal\":{\"name\":\"Noble and Precious Metals - Properties, Nanoscale Effects and Applications\",\"volume\":\"14 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-12-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"20\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Noble and Precious Metals - Properties, Nanoscale Effects and Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5772/INTECHOPEN.70901\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Noble and Precious Metals - Properties, Nanoscale Effects and Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5772/INTECHOPEN.70901","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Applications of Gold Nanoparticles in Cancer Imaging and Treatment
Cancer is one of the leading causes of death worldwide. In the last two decades, the development of nanotechnology has facilitated our ability to design new nanoparticles for the diagnosis and treatment of cancer. In this chapter, we reviewed the applications of gold nanoparticles as contrast agents for cancer imaging, including optical imaging, photoacoustic imaging, and X-ray–based imaging. We also reviewed their applications as delivery carriers for small molecule drugs, therapeutic genes, vaccines, and adjuvants and as therapeutic agents by themselves in cancer treatment, including photothermal therapy, photodynamic therapy, and radiation therapy.