[患放射病的大鼠大脑中磷脂代谢的几个方面的变化]。

Voprosy biokhimii mozga Pub Date : 1976-01-01
A A Agababova, K G Karagezian
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引用次数: 0

摘要

亚致死剂量(400)和致死剂量(1600)伦琴使大鼠脑中性磷脂水平降低,酸性磷脂水平升高。随着放射病的发展,游离甘油和甘油磷酸含量增加,甘油激酶和甘油磷酸生物合成的糖酵解途径被激活,甘油磷酸脱氢酶催化的正反反应加剧。大鼠脑磷脂提取物制备的人工双分子磷脂膜的通透性在辐照结束时显著增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Shifts in several aspects of phospholipid metabolism in the brains of white rats with radiation sickness].

Sublethal (400) and lethal (1600) doses of roentgen decrease the level of neutral phospholipids of rat brain and increase that of acid phospholipids. With the development of radiation disease the content of free glycerine and glycerophosphate increases and the glycerokinase and glycolytic pathways of glycerophosphate biosynthesis are activated together with the intensification of the direct and reverse reactions catalyzed by glycerophosphate dehydrogenase. The permeability of the artificial bimolecular phospholipid membranes prepared from rat brain phospholipid extracts is significantly increased at the end of the radiation.

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