L. Bour, A. Wolzak, D. van’t Ent, J. Speelman, B. W. Ongerboer de Visser
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引用次数: 1
摘要
用C. a . Scudder(1988)提出的跳跃式脉冲发生器模型进行计算机模拟表明，在不改变脉冲发生器本身特性的情况下，可以改变跳跃式脉冲的度量及其速度特性。该模型可用于解释例如帕金森病(PD)的跳眼运动损伤，因为在这种疾病中，脑干水平的脑桥结构(即爆发发生器所在的位置)不受影响。PD患者的扫视与计算机模拟的比较表明，该模型对观察到的最大扫视速度降低提供了合理的解释，但不适合解释扫视的低视。
Computer Simulution Of Oculomotor Control In extrapyranidal Disorders
Computer simulation with a model of the saccadic burst generator, proposed by C. A. Scudder (1988), demonstrated that metrics of saccades as well as their velocity characteristics can be altered without changing the characteristics of the burst generator itself. The model could be used to explain impairment of saccadic eye movements in, for instance, Parkinson's disease (PD), since in this disorder at brainstem level pontine structures, where the burst generator is located, are unaffected. Comparison of saccades in PD patients with computer simulations showed that the model provided reasonable explanation for the observed reduction in maximum saccade velocity, but is not appropriate to explain hypometria of saccades.
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