新的基于哈希的序列对齐算法

Fan Peng, T. Yao, Zhenhui Wang, Jeffrey Zheng, Guangyu Yue
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引用次数: 0

摘要

随着人类对疾病认识的逐渐深入和诊疗水平的不断提高,精准医学作为一种新的医学概念医学模式被提出。高通量、高精度的基因序列读取和高精度、快速的基因序列比对为精准医学的诊断和治疗提供了依据。提出了一种基于矩阵和链表的序列信息存储方法。将这两个哈希函数的哈希值作为序列在矩阵中的坐标值,利用它们可以找到目标序列。将该算法与五种经典的比较算法进行了比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New Hash-based Sequence Alignment Algorithm
With the gradual deepening of human understanding of the disease and the continuous improvement of diagnosis and treatment, precision medicine, a new medical concept medical model, has been proposed. High-throughput and high-accuracy gene sequence reading and high-accuracy and rapid gene sequence alignment provide the basis for diagnosing and treating precision medicine. This paper presents a new method based on matrix and linked-list to store sequence information. The hash values of the two hash functions are used as the coordinate values of the sequence in the matrix, and they can be used to find the target sequence. The algorithm is compared with five classical comparison algorithms.
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