二维基质中胶原纳米纤维的循环拉伸排列

2015 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS) Pub Date : 2015-03-02 DOI:10.1109/MEMSYS.2015.7050991

Eunryel Nam, Won Chul Lee, S. Takeuchi

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引用次数: 1

摘要

本文提出了一种制备二维胶原蛋白片的新方法，其内部分子结构在一个方向上形成高度排列的纳米纤维。在本研究中，通过在胶原溶液凝胶化过程中施加循环拉伸，胶原纳米纤维在完全二维基质中自排列，并且在所制备的胶原片中诱导细胞在培养期间没有任何机械力的情况下排列。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Alignment of collagen nanofibers in 2D substrates using cyclic stretch

This paper presents a new method to fabricate 2-dimensional collagen sheets whose internal molecular structures form highly-aligned nanofibers in one direction. In this work, collagen nanofibers are self-aligned in fully 2-dimensional substrates by applying cyclic stretch during the gelation process of collagen solution, and the fabricated collagen sheets induce the alignment of cells without any mechanical force within the cultivation period.

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2015 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

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