经蝶鞍经蝶窦入路治疗鞍上脑膜瘤

John Jane Jr.1, Aaron Dumont1, Mary Vance2, Edward Laws Jr.1
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引用次数: 27

摘要

经蝶窦入路是切除垂体瘤的首选方法。鞍上肿瘤也可经蝶窦入路,以扩大蝶鞍为背景。鞍上肿瘤呈纤维状且不伴有鞍扩张者通常采用开颅术治疗。然而,经颅切除鞍上脑膜瘤对视器官有很大的危险。经蝶窦入路可改良为鞍上脑膜瘤的切除提供通路。我们回顾了一系列连续的鞍上脑膜瘤患者经蝶窦鞍上脑膜入路。从2000年1月到2002年7月,6例患者接受了经蝶窦经蝶窦入路。所有患者术前和术后均接受了全面的眼科和内分泌检查。所有患者术前、术后6周至3个月、每年进行磁共振成像。2例患者表现为视力障碍,1例有内分泌功能障碍。肿瘤直径1.5 ~ 2.5 cm,平均2.1 cm,磁共振显示交叉受压。6例患者中有4例(67%)完全切除,无复发。两名视力障碍患者的视力均有改善,一名视力正常的患者术前出现轻度双颞偏盲。83%的人视力保持正常或有所改善。无患者术后需要垂体激素替代,无患者出现脑脊液鼻漏。经鞍上脑膜瘤经鞍上脑膜入路是一种可行的替代开颅手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Transsphenoidal Transtuberculum Sellae Approach for Suprasellar Meningiomas
The transsphenoidal approach is the preferred method for removal of pituitary tumors. Suprasellar tumors may also be approached transsphenoidally in the setting of an expanded sella turcica. Suprasellar tumors that are fibrous and not associated with an expanded sella are generally treated with craniotomy. However, transcranial resection of suprasellar meningiomas carries significant risk to the optic apparatus. The transsphe-noidal approach may be modified to provide access for resection of suprasellar meningiomas. A consecutive series of patients with suprasellar meningiomas who underwent a transsphenoidal transtuberculum sellae approach were reviewed retrospectively. From January 2000 to July 2002, six patients underwent the transsphenoidal transtuberculum sellae approach. All patients underwent thorough preoperative and postoperative ophthalmologic and endocrinologic testing. Magnetic resonance imaging of all patients was obtained preoperatively, 6 weeks to 3 months postoperatively, and annually. Two patients presented with visual dysfunction and one had signs of endocrine dysfunction. Tumor diameter ranged from 1.5 to 2.5 cm with a mean diameter of 2.1 cm and all tumors revealed magnetic resonance evidence of chiasmatic compression. Gross total resection was accomplished in four of six (67%) patients and no patient has experienced recurrence. Vision improved in both patients who presented with visual dysfunction and one patient with normal vision preoperatively experienced a mild bitemporal hemianopsia. Vision remained normal or improved in 83%. No patient required pituitary hormone replacement postoperatively and no patient experienced cerebrospinal fluid rhinorrhea.The transsphe-noidal transtuberculum sellae approach represents a viable alternative to craniotomy for selected suprasellar meningiomas.
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