Cardiorespiratory parameters monitoring during moderate sedation at different oxygen flow rates in patients undergoing endoscopic intervention

Background: Cardiorespiratory parameters before, during and after administration of sedation/analgesia in patients undergone endoscopic procedure should have monitored. Aim of the study: In this study we evaluated the effect of different O2 flow rates on the non-invasive CO2 monitoring (EtCO2) in patients that are breathing spontaneously under moderate sedation undergoing endoscopic procedures. Methods: 120 patients of both sexes aged between 25 and 60 years with ASA- I and II scheduled for undergoing upper GIT endoscopy for gastric ulcer patients. Patients were randomized to three equal groups. Group I: 40 patients will receive O2 supply at rate of 2 liters per minute and then cabnographic and other measures will be recorded throughout the procedure. Group II: 40 patients will receive O2 supply at rate 4 liters per minute and then cabnographic and other measures will be recorded throughout the procedure. Group III: 40 patients will receive O2 supply at rate 6 liters per minute and then cabnographic and other measures will be recorded throughout the procedure. Results: EtCO2 differences between the three studied groups were statistically significant at preoperative, induction, 5, 10, 20 and 30 min but with no any clinical significance or adverse outcome. HR, MBP, RR and Spo2 difference between group were statistically insignificant throughout the procedure with no serious complications were recorded and patients satisfaction results were comparable between the three studied groups. Conclusion: Our study demonstrated that different O2 flow rates did not affect noninvasive EtCO2 measurement during moderate sedation in patients undergoing upper GIT endoscopy for gastric ulcer patients.