风湿病/ILD联合服务。伍尔弗汉普顿体验

A. Zahid, P. Chohan, T. Sheeran, A. Fahim
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摘要

在风湿病的背景下,间质性肺疾病(ILD)呈现出难以诊断和管理的挑战。风湿病- ild联合服务有可能改善CTD-ILD的临床结果。新十字医院是一家大型地区综合医院,于2014年开始提供这项服务,我们提供了两年的审计数据。目的:评价新十字医院风湿病/ILD联合服务的有效性。方法:回顾性分析2014年1月- 2015年12月2年的CTD-ILD临床资料。78例已知CTD的患者,由风湿病学和呼吸学顾问在联合临床环境中就诊。所有患者HRCT胸部检查均证实肺纤维化。结果:78例患者中,10例(12%)患者经临床复查后诊断发生改变。所有患者(100%)在第一次联合临床复查后均有完整的肺功能。25例(32%)患者的治疗方法发生了变化,其中5例接受静脉注射环磷酰胺治疗,19例泼尼松龙剂量增加,1例接受利妥昔单抗治疗。没有患者被认为是肺移植的合适人选。所有患者在第一次门诊预约时要求进行经胸超声心动图检查以筛查肺动脉高压。结论:风湿病学/ILD联合服务减少了CTD-ILD患者的门诊预约次数。此外,它改变了相当比例患者的临床管理,提高了诊断准确性和临床治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Combined Rheumatology/ILD Service. The Wolverhampton Experience
Introduction: Interstitial lung diseases (ILD), in the context of rheumatological disorders, present difficult diagnostic and management challenges.A combined rheumatology-ILD service has a potential to improve clinical outcomes in CTD-ILD. New Cross Hospital, a large district general hospital commenced providing this service in 2014 and we present an audit data over a 2 year period. Aims: To assess the effectiveness of combine rheumatology/ILD service at New Cross Hospital. Methods: A retrospective analysis of CTD-ILD clinic data over 2 years (January 2014- December 2015) was carried out. 78 patients, with known CTD, seen by both rheumatology and respiratory consultants in a combined clinical setting. All patients had proven pulmonary fibrosis on HRCT Chest. Results: Of the 78 patients, 10 patients (12%) had change in the diagnosis after clinic review. All patients (100%) had full lung functions after their first combined clinic review. Twenty five patients (32%) had a change in their management, (5 were treated with IV cyclophosphamide, 19 had an increase in prednisolone dosage while one patient received rituximab). No patient was felt to be a suitable candidate for lung transplantation. All patients had a transthoracic echocardiogram requested at their first clinic appointment to screen for pulmonary hypertension. Conclusions: Combined Rheumatology/ILD service reduces number of outpatient clinic appointments for patients with CTD-ILD. Moreover, it alters clinical management in a significant proportion of patients, improving diagnostic accuracy and clinical therapeutics.
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