微波消融技术在肿瘤治疗中的应用:不同槽位的单槽微波消融模拟

A. Razib, K.A. Hossain, S. Hossain
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引用次数: 7

摘要

微波消融(MWA)是杀死癌细胞的有效方法之一。在这个过程中,辐射集中在所需的区域,确保适当的温度分布,而不损害周围的组织。为了有效地治疗癌症,可以使用槽同轴天线来产生吸热和温度分布模型。研究表明,当天线槽位在肿瘤的50%位置时,可以获得更高的SAR值(峰值SAR约5.78 kW/kg)和更大的热消融面积;当改变槽位位置时,更多的好细胞被破坏,但改变槽位位置也会降低温度(当槽位位置为50%时,乳房组织内的最高温度为203℃,持续时间为t = 2 min,而当槽位位置为25%和75%时,乳房组织内的最高温度分别为156℃和185℃)。最后,研究结果表明,对于所设计的槽同轴天线,在2.45GHz和10W功率下;为达到最佳效果和有效影响,应在50%槽位继续微波加热2分钟;更少的时间不能覆盖所有的肿瘤细胞,改变槽的位置会导致损伤更多的好细胞。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microwave ablation technique (MWA) for cancer treatment: Simulation of single Slot MCA for different slot position
One of the effective options to kill cancer cell is Microwave ablation (MWA). In this process radiation is focused on the desired areas, ensuring appropriate temperature distribution without damaging the surrounding tissues. To effectively treat cancer, Slot coaxial antennas can be used for producing a heat absorption and temperature distribution model. In this work, it is has been demonstrated that when the antenna slot position is at 50% of the tumor higher SAR value (about 5.78 kW/kg peak SAR) and larger heat ablation area is achieved; while changing the slot position more good cells get destroyed but changing slot position also decreases temperature (The maximum temperature within the breast tissue is 203°C for 50% slot position for t = 2 min and for the same duration of time 156°C and 185°C were found for 25% and 75% slot position respectively). Lastly the results reveals that for the presented Slot Coaxial Antenna at 2.45GHz and 10W power; for optimized and efficient impact, the microwave heating should be continued for 2 min at 50% slot position; less time would not cover all the tumor cell and changing the slot position will result in damaging more good cells.
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