Antibiotic Resistance and Associated Factors with Purulent Skin Infections Due to Staphylococcus Aureus

infections are due to Staphylococcus aureus and β-hemolytic streptococci, primarily Streptococcus pyogenes [1–2]. Staphylococcus aureus is the predominant pathogen identified in skin infection Abstract Background: Purulent skin infections due to Staphylococcus aureus are common in hospitals and are frequently due to secondary bacterial infections. The aims of this study were to evaluate antibiotic resistance and to describe the factors associated with Staphylococcus aureus purulent skin infections. Methods: This is a descriptive and cross-sectional study of 179 results of cytobacteriological examinations of pus over a period of 18 months, from January 2021 to June 2022, at the laboratory of the University Hospital of Befelatanana. Results: Among the 179 cytobacteriological examinations of pus, 131 cases were positive showing a hospital prevalence of 73.2%. Among the germs identified, 46 cases (25.7%) were represented by isolates of Staphylococcus aureus . Regarding the associated factors, subjects aged 60 and over (30%) (p=0.32; NS), women (32.8%) (p=0.11; NS) and patients hospitalized in Internal Medicine departments (39.3%)(p=0 .02) were the most affected by Staphylococcus aureus purulent skin infections. Concerning the results of the antibiograms, the resistances of the isolates of Staphylococcus aureus to Penicillin G (97.8%), to Doxycycline (56.5%) and to Cotrimoxazole (41.3%) were the highest. Methicillin-resistant Staphylococcus aureus isolates were rare (4.3%) and all isolates were susceptible to Vancomycin. Conclusion