联合累西腓治疗1039例新冠肺炎患者的经验

M. Valença, M. Fonseca, Cátia Arcuri Branco, Alex Maurício Garcia Santos, A. Oliveira, Danilo Ferreira Nunes, Ana Carolina Chiappetta Correia de Araújo, F. Cruz
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In the same period, we evaluated the number of patients with Covid-19 or suspected Covid-19 who were seen in the emergency room at Hospital Unimed Recife III.ResultsOne hundred twenty-six thousand five hundred fifty-three patients were seen in the Emergency Unit of Hospital Unimed Recife III in the period between March 26, 2020, and January 31, 2021; of those 126,553 patients seen in the emergency 39,340 (31.09%) patients were diagnosed with having Covid-19 or suspected of Covid-19. In the 10-month period, 1,039 patients with Covid-19 were hospitalized, 61% with hypertension, 31.1% with SARS, 30.0% with diabetes, and 9.9% were obese. The average hospital stay was 11.2 days. 342/1,039 (32.9%) patients were admitted to the ICU, and 57.9% of them had mechanical ventilation. The overall lethality was 13.76% (143 deaths/1,039 inpatients). An increase in lethality by Covid-19 was associated with increased age. 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引用次数: 1

摘要

目的描述巴西累西腓联合医院收治的新冠肺炎患者的相关特征,评估这些患者的人口统计数据、致死率、机械呼吸机的使用、相关疾病的存在、使用ICU的必要性以及与预后相关的其他方面。方法从DRG巴西健康管理平台收集数据,包括从2020年3月16日第一例Covid-19患者入住达联合III医院到2021年1月31日的数据。所有在联合累西腓三所医院之一(联合累西腓第一医院、联合累西腓第三医院和联合累西腓综合医院)住院的患者都被纳入研究。在同一时期,我们评估了在联合累西腓第三医院急诊室就诊的Covid-19患者或疑似Covid-19患者的数量。结果2020年3月26日至2021年1月31日,联合累西腓第三医院急诊科共收治患者1226553例;在紧急情况下就诊的126553名患者中,有39340名(31.09%)患者被诊断患有Covid-19或疑似Covid-19。在10个月的时间里,1039名新冠肺炎患者住院,其中61%为高血压,31.1%为SARS, 30.0%为糖尿病,9.9%为肥胖。平均住院时间为11.2天。1039例患者中有342例(32.9%)入住ICU,其中机械通气占57.9%。总死亡率为13.76%(143例死亡/ 1039例住院患者)。Covid-19致死率的增加与年龄的增长有关。与大流行的最后5个月相比,新冠肺炎大流行初期的致死率明显更高(17.6%对9.7%)。肥胖显著增加了Covid-19患者的致死率[120例死亡/ 1016例非肥胖患者(11.8%)vs 23例死亡/103例肥胖患者(22.3%),OR 2.15 (1.30 - 3.50), p = 0.005)]。结论2019冠状病毒病是一种预后较差的疾病,尤其是在老年和肥胖患者中。在Covid-19大流行的第二个5个月期间,我们注意到Covid-19在住院患者中的致死率显著降低。Covid-19是一种新疾病,病毒繁殖的机制或感染生物体的病理生理过程如何发生仍然知之甚少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unimed Recife's experience in treating 1,039 patients with Covid-19
ObjectiveTo describe the features related to patients with Covid-19 admitted to Unimed Recife hospitals, Recife, Brazil, evaluating demographic data, lethality, use of a mechanical ventilator, presence of associated diseases, the need to use the ICU, among other aspects related to the prognosis of these patients.MethodData were collected from the DRG Brazil health management platform, including the period from March 16, 2020, when the first patient with Covid-19 was admitted to the Hospital da Unimed III, until January 31, 2021. All patients admitted to one of the three hospitals of Unimed Recife - Hospital Unimed Recife I, Hospital Unimed Recife III, and Hospital Geral Unimed Recife – were included in the study. In the same period, we evaluated the number of patients with Covid-19 or suspected Covid-19 who were seen in the emergency room at Hospital Unimed Recife III.ResultsOne hundred twenty-six thousand five hundred fifty-three patients were seen in the Emergency Unit of Hospital Unimed Recife III in the period between March 26, 2020, and January 31, 2021; of those 126,553 patients seen in the emergency 39,340 (31.09%) patients were diagnosed with having Covid-19 or suspected of Covid-19. In the 10-month period, 1,039 patients with Covid-19 were hospitalized, 61% with hypertension, 31.1% with SARS, 30.0% with diabetes, and 9.9% were obese. The average hospital stay was 11.2 days. 342/1,039 (32.9%) patients were admitted to the ICU, and 57.9% of them had mechanical ventilation. The overall lethality was 13.76% (143 deaths/1,039 inpatients). An increase in lethality by Covid-19 was associated with increased age. Lethality in the first period of the Covid-19 pandemic was significantly higher when compared to the last 5 months of the pandemic(17.6% versus 9.7%). Obesity significantly increased lethality in patients with Covid-19 [120 deaths/1,016 non-obese patients (11.8%) versus 23 deaths/103 obese patients (22.3%), OR 2.15 (1.30 - 3.50), p = 0.005)].ConclusionWe conclude that Covid-19 is a disease with a poor prognosis, especially in the elderly and obese patients. In the second 5-month period of the Covid-19 pandemic, we noticed a significant reduction in lethality by Covid-19 in hospitalized patients. Covid-19 is a new disease and the mechanism by which the viruses multiply or how the pathophysiological process occurs in the infected organism are still barely understood.
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