用于前列腺成像的紧凑型正电子断层扫描机的概念设计

J. Huber, S. Derenzo, J. Qi, W. Moses, R. Huesman, T. Budinger
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引用次数: 24

摘要

汇总表只收到如下内容。作者提出了一种用于前列腺成像的紧凑型正电子断层扫描仪的概念设计,使用一对放置在患者上方和下方的外部弯曲检测器组。下方的检测器组固定在病床下方,顶部的检测器组垂直调整,以获得最大的灵敏度和患者访问。每个银行由40个HR+PET块探测器组成,形成两个弧形(44 cm小轴,/spl sim/60 cm长轴),倾斜以减少衰减,并尽可能靠近患者以提高灵敏度。单个探测器的角度指向前列腺,以尽量减少该区域的分辨率下降。平面间间隔延伸/spl sim/ 5cm以上的闪烁晶体,以减少随机和散射背景。为了使成本最小化,患者没有被检测器环完全包围,由于侧面间隙导致采样不完整。蒙特卡罗模拟(包括随机和分散)证明了检测直径为2.5 cm的球形肿瘤的可行性,肿瘤与背景的比例为2:1,需要在注射10 mCi(例如碳-11胆碱)后2分钟扫描即可实现的计数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Conceptual design of a compact positron tomograph for prostate imaging
Summary form only received as follows. The authors present a conceptual design of a compact positron tomograph for prostate imaging, using a pair of external curved detector banks placed above and below the patient. The lower detector bank is fixed below the patient bed, and the top bank adjusts vertically for maximum sensitivity and patient access. Each bank is composed of 40 HR+PET block detectors, forming two arcs (44 cm minor, /spl sim/60 cm major axis) that are tilted to minimize attenuation and positioned as close as possible to the patient to improve sensitivity. The individual detectors are angled to point towards the prostate to minimize resolution degradation in that region. Inter-plane septa extend /spl sim/5 cm beyond the scintillator crystals to reduce random and scatter backgrounds. A patient is not fully encircled by detector rings in order to minimize cost, causing incomplete sampling due to the side gaps. Monte Carlo simulation (including randoms and scatter) demonstrates the feasibility to detect a spherical tumor of 2.5 cm diameter with a tumor to background of 2:1, requiring a number of counts that should be achievable with a 2 minute scan after a 10 mCi injection (e.g. carbon-11 choline).
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