{"title":"将all转换为aml是一种罕见的现象","authors":"M. Kishore, Vijay Kumar, S. Marwah, A. Nigam","doi":"10.32677/IJCR.2019.V05.I02.019","DOIUrl":null,"url":null,"abstract":"Among all acute leukemias, acute lymphoblastic leukemia (ALL) is five times more common than acute myeloid leukemia (AML). Lineage switch from ALL to AML is very rare. Lineage switching is a phenomenon noted in cases of leukemias where the initially diagnosed cases of leukemias of a lineage (lymphoid/myeloid) present with the opposite lineage at relapse. Here, we report the case of a 10-year-old male child who was initially diagnosed with ALL and on relapse after 4 years, presented with AML. The blast cell morphology and immunophenotype were consistent with the diagnosis of typical AML.","PeriodicalId":130971,"journal":{"name":"Volume 5, Issue 2, Mar - Apr 2019","volume":"40 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"CONVERSION OF ALL TO AML: A RARE PHENOMENON\",\"authors\":\"M. Kishore, Vijay Kumar, S. Marwah, A. Nigam\",\"doi\":\"10.32677/IJCR.2019.V05.I02.019\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Among all acute leukemias, acute lymphoblastic leukemia (ALL) is five times more common than acute myeloid leukemia (AML). Lineage switch from ALL to AML is very rare. Lineage switching is a phenomenon noted in cases of leukemias where the initially diagnosed cases of leukemias of a lineage (lymphoid/myeloid) present with the opposite lineage at relapse. Here, we report the case of a 10-year-old male child who was initially diagnosed with ALL and on relapse after 4 years, presented with AML. The blast cell morphology and immunophenotype were consistent with the diagnosis of typical AML.\",\"PeriodicalId\":130971,\"journal\":{\"name\":\"Volume 5, Issue 2, Mar - Apr 2019\",\"volume\":\"40 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-04-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Volume 5, Issue 2, Mar - Apr 2019\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32677/IJCR.2019.V05.I02.019\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Volume 5, Issue 2, Mar - Apr 2019","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32677/IJCR.2019.V05.I02.019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Among all acute leukemias, acute lymphoblastic leukemia (ALL) is five times more common than acute myeloid leukemia (AML). Lineage switch from ALL to AML is very rare. Lineage switching is a phenomenon noted in cases of leukemias where the initially diagnosed cases of leukemias of a lineage (lymphoid/myeloid) present with the opposite lineage at relapse. Here, we report the case of a 10-year-old male child who was initially diagnosed with ALL and on relapse after 4 years, presented with AML. The blast cell morphology and immunophenotype were consistent with the diagnosis of typical AML.
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