黄疸性质对急性胰腺炎治疗策略的影响

T. Tamm, V. V. Nepomnyaschiy, K. Kramarenko, I. Mamontov, O. P. Zakharchuk, I. Zulfigarov, D. D. Ryabushenko
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摘要

摘要本研究旨在通过提高合并黄疸性质的鉴别诊断质量,提高AP合并黄疸综合征患者的治疗效果。研究材料和方法。分析52例急性胰腺炎合并黄疸综合征患者的治疗结果,其中机械性黄疸42例(80.9%),实质性黄疸10例(19.1%)。结果和讨论。42例因十二指肠大乳头结块、胆总管结石、乳头炎引起的急性胰腺炎、机械性黄疸患者中,28例行内镜下乳头括约肌切开术并鼻胆管引流。7例因结痂较大,行开腹胆囊切除术联合胆总管取石及十二指肠后间隙引流术。21例行LChE, 14例胆囊颈炎性浸润压迫肝总管行选择性腹腔镜胆囊切除术。急性胰腺炎和机械性黄疸患者组无死亡病例。急性胰腺炎合并实质黄疸组10例死亡4例,死亡率为40%。结论。急性胰腺炎机械性黄疸和实质性黄疸的鉴别诊断需要超声,可以确定治疗策略、手术类型和保守治疗的程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
INFLUENCE OF JAUNDICE NATURE ON THE TREATMENT TACTICS OF PATIENTS WITH ACUTE PANCREATITIS
Abstract. The aim of the study is to improve the treatment results of patients with AP with jaundice syndrome by improving the quality of differential diagnosis of the nature of concomitant jaundice. Materials and methods of research. The treatment results of 52 patients with acute pancreatitis complicated by jaundice syndrome were analyzed, jaundice was mechanical in 42 (80.9 %) cases, parenchy-mal – in 10 (19.1 %). Results and discussion. 28 from 42 patients with acute pancreatitis and mechanical jaundice caused by concretion in the large duodenal papilla, choledocholithiasis and papillitis underwent endoscopic papillosphincterotomy with nasobiliary drainage. In 7 cases open cholecystectomy with choledocholithotomy and retroduodenal space drainage were performed due to the large size of concretions. LChE was performed in 21 case, elective laparoscopic cholecystectomy was performed in 14 patients with compression of the common hepatic duct by inflammatory infiltrate in the gallbladder neck. There were no fatalities in the group of patients with acute pancreatitis and mechanical jaundice. In the group of patients with acute pancreatitis and parenchymal jaundice 4 from 10 patients died, mortality was 40 %. Conclusions. Ultrasound is required for differential diagnosis of mechanical and parenchymal jaundice in acute pancreatitis, which allows the determination of the treatment tactics, type of surgery and the extent of conservative therapy.
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