Neurocutaneous Melanocytosis: Cytological, Clinical and Radiological Assessment in a Patient Presented with Congenital Melanocytic Nevi and Seizure Disorder: Case Report and Review of the Literature

Neurocutaneous Melanocytosis (NCM) is a rare congenital disorder characterized by multiple melanocytic nevi scattered all over the body, in addition to leptomeninges. It is suggested that NCM is developed due to abnormal proliferation of melanin-producing cells following dysmorphogenesis in the embryology life. The clinical symptoms of NCM depend on the size and site of the lesion. One of the most common sites is the anterior temporal lobe. Management options are limited in such patient and the prognosis is generally poor. Clinical, radiological, along with CSF cytology can establish the diagnosis of NCM. Surgical intervention carries temporary better results than adjuvant therapy in patients with NCM.