{"title":"声动力疗法:致命脑肿瘤的一种新兴治疗方法","authors":"E. Benaim","doi":"10.14229/onco.2023.07.25.001","DOIUrl":null,"url":null,"abstract":"Researchers and clinicians have made great strides against many cancers but, unfortunately, not all of them. Glioblastoma multiforme (GBM) remains incredibly deadly – the five-year survival rate is a meager 5%. Diffuse intrinsic pontine glioma (DIPG) is an almost universally fatal pediatric brain tumor. The five-year survival is around 2%. GBMs are generally treated with surgery and radiation. DIPG is so thoroughly embedded in the pons that surgery is impossible. Radiation can provide some small relief, and clinicians have seen some promise in CAR-T therapy. [3] However, the gains are uncertain and the cost in side effects quite high.","PeriodicalId":301370,"journal":{"name":"Onco Zine – The International Oncology Network","volume":"215 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sonodynamic Therapy: An Emerging Treatment for Deadly Brain Tumors\",\"authors\":\"E. Benaim\",\"doi\":\"10.14229/onco.2023.07.25.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Researchers and clinicians have made great strides against many cancers but, unfortunately, not all of them. Glioblastoma multiforme (GBM) remains incredibly deadly – the five-year survival rate is a meager 5%. Diffuse intrinsic pontine glioma (DIPG) is an almost universally fatal pediatric brain tumor. The five-year survival is around 2%. GBMs are generally treated with surgery and radiation. DIPG is so thoroughly embedded in the pons that surgery is impossible. Radiation can provide some small relief, and clinicians have seen some promise in CAR-T therapy. [3] However, the gains are uncertain and the cost in side effects quite high.\",\"PeriodicalId\":301370,\"journal\":{\"name\":\"Onco Zine – The International Oncology Network\",\"volume\":\"215 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Onco Zine – The International Oncology Network\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14229/onco.2023.07.25.001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Onco Zine – The International Oncology Network","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14229/onco.2023.07.25.001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Sonodynamic Therapy: An Emerging Treatment for Deadly Brain Tumors
Researchers and clinicians have made great strides against many cancers but, unfortunately, not all of them. Glioblastoma multiforme (GBM) remains incredibly deadly – the five-year survival rate is a meager 5%. Diffuse intrinsic pontine glioma (DIPG) is an almost universally fatal pediatric brain tumor. The five-year survival is around 2%. GBMs are generally treated with surgery and radiation. DIPG is so thoroughly embedded in the pons that surgery is impossible. Radiation can provide some small relief, and clinicians have seen some promise in CAR-T therapy. [3] However, the gains are uncertain and the cost in side effects quite high.
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