E. P. Stranadko, M. Riabov, N. N.VoIkova, S. Spaniol, W. Rauschning, N. Nifantiev
{"title":"新型光敏剂氯e6衍生物a (blc1010)光动力治疗效果的试验","authors":"E. P. Stranadko, M. Riabov, N. N.VoIkova, S. Spaniol, W. Rauschning, N. Nifantiev","doi":"10.1364/ecbo.2001.4433_155","DOIUrl":null,"url":null,"abstract":"Efficacy of PDT with new chlorin e6 photosensitizer (BLC 1010) has been tested in 72 cancer patients. 44 patients (61 %) achieved a complete response and 39 % of the patients a partial response (28 patients, including 15 patients treated for palliation).\n Rapid elimination of BLC 1010 from the organism solves the problem of skin phototoxicity encountered in PDT up to now. This property together with its high tumor to normal ratio makes it a promising photosensitizer for PDT. Further advantage is that portable diode lasers with proper wavelength are available.","PeriodicalId":421041,"journal":{"name":"Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy","volume":"86 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Testing of efficacy of photodynamic therapy with a new photosensitizer - a of chlorin e6 derivative (BLC 1010)\",\"authors\":\"E. P. Stranadko, M. Riabov, N. N.VoIkova, S. Spaniol, W. Rauschning, N. Nifantiev\",\"doi\":\"10.1364/ecbo.2001.4433_155\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Efficacy of PDT with new chlorin e6 photosensitizer (BLC 1010) has been tested in 72 cancer patients. 44 patients (61 %) achieved a complete response and 39 % of the patients a partial response (28 patients, including 15 patients treated for palliation).\\n Rapid elimination of BLC 1010 from the organism solves the problem of skin phototoxicity encountered in PDT up to now. This property together with its high tumor to normal ratio makes it a promising photosensitizer for PDT. Further advantage is that portable diode lasers with proper wavelength are available.\",\"PeriodicalId\":421041,\"journal\":{\"name\":\"Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy\",\"volume\":\"86 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1364/ecbo.2001.4433_155\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/ecbo.2001.4433_155","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Testing of efficacy of photodynamic therapy with a new photosensitizer - a of chlorin e6 derivative (BLC 1010)
Efficacy of PDT with new chlorin e6 photosensitizer (BLC 1010) has been tested in 72 cancer patients. 44 patients (61 %) achieved a complete response and 39 % of the patients a partial response (28 patients, including 15 patients treated for palliation).
Rapid elimination of BLC 1010 from the organism solves the problem of skin phototoxicity encountered in PDT up to now. This property together with its high tumor to normal ratio makes it a promising photosensitizer for PDT. Further advantage is that portable diode lasers with proper wavelength are available.
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