Body Surface Laplacian Mapping In Man

We have developed a new approach to improve the spatial resolution of body surface mapping of cardiac electrical activity by measuring the surface Laplacian of the body surface potential. A high resolution body surface Laplacian mapping system has been developed and successfully applied to study the Laplacian maps of noxmal human subjects. Both simulation and experimental studies have shown that the body surface Laplacian mapping provides much better spatial resolution than potential mapping. This may enable Laplacian mapping to identify from the body surface spatially separated myocardial events, and to play a signifcant role in quantitative cardiac electrophysiology. superior spatial resolution in identifying multiple sources in the heart [SI. In the present study, we have developed a special bipolar 'Laplacian' electrode to sense the surface Laplacian and a high resolution mapping system to measure the BSLM. The developed techniques have been successfully applied to map the cardiac electrical events in normal human subjects and will be described in this paper.